Dr. Stefanie Wege

Dr. Stefanie Wege

INRES - Plant Nutrition
Karlrobert-Kreiten-Strasse 13
D-53115 Bonn

ORCID: 0000-0002-7232-5889
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Research interests

I am interested in plant nutrition and plant stress tolerance; with a special focus on the role of endomembrane ion transporters and the integration of ion transport across different membranes. I am particularly interested in ion transporters in small compartments of the endomembrane system, such as the Endoplasmic Reticulum, Golgi and Trans-Golgi-Network/Early-Endosome. Loss of such ion transporters leads to severe phenotypic defects, in the model plant Arabidopsis but also in crops such as rice and soybean. The aim of my research is to decipher the cellular roles of endomembrane ion transporters and to elucidate their role in plants and how they contribute to improved stress tolerance.

Positions held

seit 2022

Senior Scientist, University of Bonn, Germany

2017-2021

Lecturer, University of Adelaide, Australia

2014-2016

Postdoc, University of Adelaide, Australia

2011-2014

Postdoc, University of Lausanne, Switzerland

Selected publications

McKay D.W., McFarlane H.E., Qu Y., Situmorang A., Gilliham M., Wege S.* (2022) Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1). eLife, 11: e70701. *corresponding author

Qu Y., Yu L., Rongxia G., Berkovitz O., David R., Whelan J., Ford M., Wege S.*, Qiu L.*, Gilliham M.* (2022) Enhanced reactive oxygen detoxification occurs in salt-stressed soybean roots expressing GmSALT3. Physiologia Plantarum, 174: e13709. *co-corresponding author

Wege S., Qui J., Byrt .C.S., Houston K., Waugh R., Gilliham M., Hrmova M. (2021) A single residue deletion in the barley HKT1; 5 P189 variant restores plasma membrane localisation but not Na+ conductance. Biochimica et Biophysica Acta Biomembranes, 1863: 183669.

Qu Y., Guan R., Bose J., Jiang J., Henderson S.W., Wege S.*, Qiu L.*, Gilliham M.* (2021) Soybean CHX protein GmSALT3 confers leaf Na+ exclusion via a root derived mechanism, and Cl− exclusion via a shoot derived process, Plant, Cell and Environment, 44: 856–869. *co-corresponding author

David R., Byrt C.S., Tyerman S.D., Gilliham M., Wege S.* (2019) Roles of membrane transporters: connecting the dots from sequence to phenotype. Annals of Botany, 124: 201-208. *corresponding author

Wege S.*, Gilliham M., Henderson S.W. (2017) Chloride: not simply a ‘cheap osmoticum’, but a beneficial plant macronutrient. Journal of Experimental Botany, 68; 3057-3069. *corresponding author

Wege S., Khan G.A., Jung J.Y., Vogiatsaki E., Pradervand S., Aller I., Meyer A.J., Poirier Y. (2016) The EXS domain of PHO1 participates in the response of shoots to phosphate deficiency via a root-to-shoot signal. Plant Physiology, 170: 385-400.

Wege S., De Angeli A., Droillard M.J., Kroniewisz L., Merlot S., Cornu D., Gambale F., Martinoia E., Barbier-Brygoo H., Thomine S., Leonhardt N., Filleur S. (2014) Phosphorylation of the vacuolar anion transporter AtCLCa is required for stomata response to abscisic acid. Science Signaling, 7: 333-65.

Wege S., Jossier M., Filleur S., Thomine S., Barbier-Brygoo H., Gambale F., De Angeli A. (2010) The proline 160 in the selectivity filter of the Arabidopsis NO3-/H+ exchanger AtCLCa is essential for nitrate accumulation in planta. Plant Journal, 63: 861-869.

Wege S., Scholz A., Gleissberg S., Becker A. (2007) Highly efficient virus-induced gene silencing (VIGS) in California poppy (Eschscholzia californica): an evaluation of VIGS as a strategy to obtain functional data from nonmodel plants. Annals of Botany, 100: 641-9.